_2025_
Characterization of atomization and delivery efficiency exogenous surfactant in preterm infant lungs using an ex vivo respiratory model
G. Kaouanea, J.F.Berret, Y. Crémillieux, N. Pinaud, M. Fayon, E. Dumas la Roche, S. Perinel, L. Leclerc, J. Pourchez
Scientific Reports, 2025, accepted
Engineered biodegradable fiber for brain metal ion regulation
T. Borisova, J. Salazar Ariza. N. Pozdnyakova, N. Krisanova, A. Pastukhov, M. Dudarenko, T. Grea, A. Montembault, I. Benkhaled, N. Pinaud, J. Deborne, Y. Crémillieux, P. De Deurwaerdere, S. Palfi, O. Tillement, L. David, F. Lux
International Journal of Biological Macromolecules, 2025, (315) 144346, doi.org/10.1016/j.ijbiomac.2025.144346
MR Imaging of Pulmonary Surfactant Distribution in a Preclinical Neonatal Lung Model
O. Marfouk, G. Kaouane, L. Leclerc, F. Munsch, B. Zhang, N. Pinaud, R. Gérard, M. Fayon, S. Périnel-Ragey, E. Dumas de la Roque, J. Pourchez, Y. Crémillieux
NMR in Biomedecine, 2025, 38(6):e70053, doi.org/10.1002/nbm.70053
_2024_
Quantitative brain T1-mapping derived from T1-weighted MRI acquisitions : a proof-of-concept study
A. Lavielle, N. Pinaud, B. Zhang, Y. Crémillieux
European Radiology Experimental, 2024, (8), 109 - DOI: 10.1186/s41747-024-00517-2
NANO-GBM trial of AGuIX nanoparticles with radiotherapy and temozolomide in the treatment of newly diagnosed Glioblastoma: Phase 1b outcomes and MRI-based biodistribution
Clinical and Translational Radiation Oncology, 2024 (Vol. 48). https://doi.org/10.1016/j.ctro.2024.100833
Quantifying gadolinium-based nanoparticle uptake distributions in brain metastases via magnetic resonance imaging
S. Bennett, C. Verry, E. Kaza, X. Miao, S. Dufort, F. Boux, Y. Crémillieux, O. de Beaumont, G. Le Duc, R. Berbec, A. Sudhyadhom
Scientific Reports, 2024 (Vol. 14, Issue 1, p. 11959). https://doi.org/10.1038/s41598-024-62389-1
Implantable theranostic device for in vivo real-time NMR evaluation of drug impact in brain tumors
J. Deborne, I. Benkhaled, V. Bouchaud, N. Pinaud and Y. Crémillieux
Scientific Reports, 2024, https://doi.org/10.1038/s41598-024-55269-1
_2022_
T1 mapping using MPRAGE acquisitions: application to the measurement of the concentration of theranostic agents in tumors
A. Lavielle, F. Boux, J. Deborne, N. Pinaud, S. Dufort, C. Verry, S. Grand, I. Tropres, C. Vecco-Garda. G. Le Duc, S. Mornet and Y. Crémillieux
Journal of Magnetic Resonance Imaging, 2022, DOI: 10.1002/jmri.28509
Editorial for “Volume-Controlled 19F MR Ventilation Imaging of Fluorinated Gas”
Y. Crémillieux
Journal of Magnetic Resonance Imaging, 2022, DOI.org/10.1002/jmri.28384
The metal brain
Ph. De Deurwaerdere, Y. Crémillieux
Journal of Neuroscience Methods, 2022, DOI.org/10.1016/j.jneumeth.2022.109777
_2021_
Implantable NMR microcoils: a new tool for exploring tumor metabolism at sub-microliter scale ?
J. Deborne, N. Pinaud, Y. Crémillieux
Metabolites, 2021, 11 (3), 176
Theranostic AGuIX nanoparticles as radiosensitizer: A phase I, dose-escalation study in patients with multiple brain metastases (NANO-RAD trial)
C. Verry, S. Dufort, J. Villa, M. Gavard, C. Iriart, S. Grand, J. Charles, B. Chovelon, J.L. Cracowski, J.L. Quesada, C. Mendoza, L. Sancey, A. Lehmann, F. Jover, J.Y. Giraud, F. Lux, Y. Crémillieux, S. McMahon, P.J. Pauwels, D. Cagney, R. Berbeco, A. Aizer, E. Deutsch, M. Loeffler, G. Le Duc, O. Tillement, J. Balosso
Radiotherapy and Oncology, 2021, Vol. 160, p. 159-165
Proton magnetic resonance spectroscopy on sub-microliter volume in rat brain using implantable NMR microcoils
J. Deborne, N. Pinaud, Y. Crémillieux
NMR in Biomedecine, 2021, 34(10), e4578
_2020_
Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective
C. Verry, S. Dufort, B. Lemasson, S. Grand, J. Pietras, I. Troprès, Y. Crémillieux, F. Lux, S. Mériaux, B. Larrat, J. Balosso, G. Le Duc, E.L. Barbier, O. Tillement
Science Advances, 2020, Vol. 6, Issue 29, p. eaay5279
Nebulised gadolinium-based nanoparticles for a multimodal approach: quantitative and qualitativelung distribution using magnetic resonance and scintigraphy imaging in isolated ventilated porcine lungs
Y. Montigaud ; J. Pourchez ; L. Leclerc ; O. Tillement ; A. Clotagatide ; C. Bal ; N. Pinaud ; N. Ichinose ; B. Zhang ; S. Perinel ; F. Lux ; Y. Crémillieux ; N. Prevot
International Journal of Nanomedicine, 2020, 30(15), 7251-7262
EPR-mediated tumor targeting using ultrasmall-hybrid nanoparticles: From animal to human with theranostic AGuIX nanoparticles
G. Bort, F. Lux, S. Dufort, Y. Crémillieux, C. Verry, O. Tillement
Theranostics, 2020, Vol. 10, Issue 3, p. 1319-1331
_2019_
Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma
A. Detappe., M. Reidy, Y. Yu, C. Mathieu, H.V.T. Nguyen, T.P. Coroller, F. Lam, P. Jarolim, P. Harvey, A. Protti, Q.D. Nguyen, J.A. Johnson, Y. Cremillieux, O. Tillement, I.M. Ghobrial, P.P. Ghoroghchian
Nanoscale, 2019, Vol. 11, Issue 43, p. 20485-20496
3D quantitative MRI of aerosolized Gd-based nanoparticules and contrast agents in isolated ventilled porcine lungs
Y. Crémillieux,Y. Montigaud, C. Bal, N. Pinaud, V.T.T Pham, F. Lux, O. Tillement, B. Zhang, J. Pourchez
Investigative Radiology, 2019, 54(12), 807
Online Quantification of Lactate Concentration in Microdialysate During Cerebral Activation Usin 1H-MRS and Sensitive NMR Microcoil
Y. Crémillieux, U. Dumond, L. Mazuel, R. Salvati, S. Rizzitelli, J. Blanc, H. Roumes, N. Pinaud, A.K. Bouzier-Sore
Frontiers in Cellular Neuroscience, 2019, 13, 89
AGuiX ® from bench to bedside-transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine
F. Lux, V.L. Tran, E. Thomas, S. Dufort, F. Rossetti, M. Martini, C. Truillet, T. Doussineau, G. Bort, F. Denat, F. Boschetti, G. Angelovski, A. Detappe, Y. Crémillieux, N. Mignet, B.T. Doan, B. Larrat, S. Meriaux, E. Barbier, S. Roux, P. Fries, A. Müller, M.C. Abadjian, C. Anderson, E. Canet-Soulas, P. Bouziotis, M. Barberi-Heyob, C. Frochot, C. Verry, J. Balosso, M. Evans, J. Sidi-Boumedine, M. Janier, K. Butterworth, S. Mcmahon, K. Prise, M.T. Aloy, D. Ardail, C. Rodriguez-Lafrasse, E. Porcel, S. Lacombe, R. Berbeco, A. Allouch, J.L. Perfettini, C. Chargari, E. Deutsch, G. Le Duc, O. Tillement
British Journal of Radiology, 2019, Vol. 92, Issue 1093, p. 20180365
_2018_
Online 1H-NMR detection and quantification of subnanomole quantities of metabolites in extracellular fluids
Y. Crémillieux, R. Salvati, U. Domond, N. Pinaud, V. Bouchaud, S. Sanchez, S. Glöggler, A. Wong
NMR in Biomedecine, 2018, 27(12), 1637-1644
Magnetic resonance imaging in animal models of respiratory diseases
N. Beckmann, Y. Crémillieux
Medical Radiology, 2018, Issue 9783319426167, p. 433-452
_2016_
In vivo online magnetic resonance quantification of absolute metabolite concentrations in microdialysate
S. Glöggler, S. Rizzitelli, N. Pinaud, G. Raffard, V. Zhendre, V. Bouchaud, S. Sanchez, A. Wong, Y. Crémillieux
Scientific Reports, 2016, 6, pp36080
Orotracheal manganese-enhanced MRI (MEMRI): An effective approach for lung tumor detection
A. Bianchi, O.L. Gobbo, S. Dufort, L. Sancey, F. Lux, O. Tillement, J.L. Coll, Y. Crémillieux
NMR in Biomedicine, 2016, Vol. 30, Issue 11, p. e3790
Morphological and quantitative evaluation of emphysema in chronic obstructive pulmonary disease patients: A comparative study of MRI with CT
D.J. Roach, Y. Crémillieux, S.D. Serai, R.P. Thomen, H. Wang, Y. Zou, R.D. Szczesniak, S. Benzaquen, J.C. Woods
Journal of Magnetic Resonance Imaging, 2016, Vol. 44, Issue 6, p. 1656-1663
Ultrashort echo-time magnetic resonance imaging is a sensitive method for the evaluation of early cystic fibrosis lung disease
D.J. Roach, Y. Crémillieux, R.J. Fleck, A.S. Brody, S.D. Serai, R.D. Szczesniak, S. Kerlakian, J.P. Clancy, J.C. Woods
Annals of the American Thoracic Society, 2016, Vol. 13, Issue 11, p. 1923-1931
MR imaging, targeting and characterization of pulmonary fibrosis using intra-tracheal administration of gadolinium-based nanoparticles
N. Tassali, A. Bianchi, F. Lux, G. Raffard, S. Sanchez, O. Tillement, Y. Crémillieux
Contrast Media and Molecular Imaging, 2016, Vol. 11, Issue 5, p. 396-404
